Table 2.
Left Heart Dimensions, Volumes, and Wall Thickness in 6.5‐Year‐Old EXPT and CTRL Children
| EXPT (n=157)a | CTRL (n=133)a | P Value | Adjusted Differences in Means (95% CI)b | P Value | |
|---|---|---|---|---|---|
| LA dimensions | |||||
| LAs length | 34.7 (5.8) | 39.3 (4.8) | <0.001 | −0.20 (−1.4 to 0.9) | 0.72 |
| LAs width | 27.2 (3.1) | 29.5 (3.3) | <0.001 | −0.7 (−1.5 to 0.1) | 0.10 |
| LA sphericity index | 1.28 (0.20) | 1.34 (0.19) | 0.009 | 0.02 (−0.03 to 0.07) | 0.38 |
| LV dimensions | |||||
| LVd length | 54.6 (4.3) | 58.6 (3.9) | <0.001 | −1.9 (−2.8 to −0.9) | <0.001 |
| LVd width | 35.6 (3.2) | 37.3 (3.2) | <0.001 | −1.0 (−1.8 to −0.3) | 0.009 |
| LV sphericity index | 1.54 (0.17) | 1.59 (0.16) | 0.03 | −0.01 (−0.05 to 0.03) | 0.62 |
| AoV annulus diameter | 13.9 (1.1) | 15.5 (1.0) | <0.001 | −0.8 (−1.0 to −0.6) | <0.001 |
| Volumes | |||||
| SV, mL | 15.8 (2.7) | 17.6 (2.9) | <0.001 | −0.8 (−1.5 to −0.02) | 0.05 |
| CO, L/min | 1.37 (0.24) | 1.47 (0.22) | 0.001 | −0.03 (−0.10 to 0.04) | 0.36 |
| Wall thickness | |||||
| IVSd | 5.6 (0.9) | 6.1 (0.8) | <0.001 | −0.1 (−0.3 to 0.1) | 0.36 |
| PWd | 5.4 (0.8) | 5.6 (0.7) | 0.004 | 0.1 (−0.1 to 0.3) | 0.50 |
| Relative WT | 0.31 (0.04) | 0.31 (0.04) | 0.98 | 0.01 (−0.002 to 0.02) | 0.09 |
| LVM, gc | 48.5 (11.4) | 59.3 (11.1) | <0.001 | −3.0 (−5.4 to −0.4) | 0.01 |
Data are shown as mean (SD) and expressed in millimeters if not indicated otherwise. AoV indicates aortic valve; CI, confidence interval; CO, cardiac output; CTRL, control (born at term); EXPT, extremely preterm; IVSd, interventricular septum thickness; LA, left atrium; LAs, left atrium in systole; LV, left ventricle; LVd, left ventricle in diastole; LVM, left ventricular mass; PWd, posterior wall thickness; SV, stroke volume; WT, wall thickness.
a
Crude values.
b
Adjusted for body surface area (m2) and site.
c
LVM calculated according to Devereux.17