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Smooth muscle cell–dependent vasodilation is not affected by risk factors or deletion of mineralocorticoid receptor (MR) in endothelial cells (EC‐MR). Sodium nitroprusside–induced relaxation in small mesenteric arteries of control, obese, and hyperlipidemic male and female MR‐intact mice (EC‐MR +/+, A and B) and EC‐MR knockout mice (EC‐MR −/−; C and D). Two‐factor ANOVA, P=not significant.
