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. 2016 Dec 5;23(2):232–254. doi: 10.1093/humupd/dmw042

Table III.

Haematoxylin and eosin section diagnostic criteria for endometrial intraepithelial neoplasia (EIN).

EIN criterion Comments
Architecture Area of glands exceeds that of stroma (VPS < 55%)
Cytology Cytology differs between architecturally crowdedfocus and background
Diameter >1 mm Maximum linear dimension of the lesion exceeds1 mm
Exclude mimics Benign conditions with overlapping criteria: basalis,secretory, polyps, repair, etc.
Exclude cancer Carcinoma if maze-like meandering glands, solidareas or appreciable cribriforming

NB: All criteria must be met in order for a diagnosis of EIN to me made.VPS = volume percentage stroma.Reproduced with permission from Baak and Mutter (2005).