Table 3.
Differential Cytokines Production by Monocyte Subsets in Response to LPS in Human and Mouse Models Relative to Mon2
| Plasma Cytokine | Mon1 | Mon2 | Mon3 |
|---|---|---|---|
| G‐CSF49, 89, 90 | High | Low | Low |
| IL‐1040, 49, 91, 92 | High | Low | Low |
| CCL227, 49, 93 | High | Low | Low |
| RANTES49, 79 | High | Low | Low |
| IL‐627, 49, 65, 88 | High | Intermediate | Intermediate |
| IL‐840, 49, 88, 90 | High | High | High |
| IL 1‐β27, 49, 65 | Intermediate | Intermediate | High |
| TNF‐α49, 65, 94 | Intermediate | Low | High |
CCR2 indicates C‐C chemokine receptor type 2; G‐CSF, granulocyte colony‐stimulating factor; IL, interleukin; LPS, lipopolysaccharide; RANTES, regulated on activation, normal T cell expressed and secreted; TNF‐α, tumor necrosis factor alpha.