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. 2018 Feb 3;7(3):e008121. doi: 10.1161/JAHA.117.008121

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Cerebral blood flow (CBF) changes after bilateral common carotid artery stenosis (BCAS) surgery. A, Representative CBF images of groups assessed by laser speckle flowmetry 6 weeks after surgery. B, Quantitative analysis of CBF indicated as arbitrary unit determined by Doppler method. CBF decreased significantly after BCAS in each group (n=7–22 for each group). *P<0.01 vs sham. ^† P<0.05 vs sham. AT₂KO indicates angiotensin II type 2 receptor knockout mice; DKO, Mas/angiotensin II type 2 receptor double knockout mice; MasKO, Mas receptor knockout mice; WT, wild‐type mice.