Table I.
Baseline characteristics of patients who received kisspeptin-54 trigger.
| N | Single | Double | Both |
|---|---|---|---|
| 31 | 31 | 62 | |
| Age (y) | 31.2 (27.9, 33.4) | 30.9 (29.1, 32.6) | 31.1 (29, 32.7) |
| Weight (kg) | 61.6 (58.4, 68.2) | 68.1 (57.4, 76.1) | 64.5 (58.4, 73) |
| Body mass index (kg/m2) | 23.9 (21.9, 27.2) | 26.6 (22.8, 28.9) | 25.5 (22.7, 28) |
| Antral follicle count (AFC) | 39 (30, 52) | 33 (29, 40) | 36 (29, 48) |
| Serum AMHa (pmol/L) | 52.4 (36, 81.4) | 44.0 (34.6, 56.4) | 45.7 (36, 63.5) |
| Number of patients with average cycle length ≥35 days number (%) | 13 (41.9%) | 11 (35.5%) | 24 (38.7%) |
| Cause of infertility | |||
| PCOSb | 17 (54.8%) | 18 (58.1%) | 35 (56.5%) |
| Tubal | 1 (3.2%) | 0 (0.0%) | 1 (1.6%) |
| Male Factor | 4 (12.9%) | 2 (6.5%) | 6 (9.7%) |
| Mixed | 1 (3.2%) | 1 (3.2%) | 2 (3.2%) |
| Idiopathic (unexplained) | 8 (25.8%) | 10 (32.3%) | 18 (29.0%) |
| Number of folliclesc | 35.0 (25.0, 44.0) | 31.0 (25.0, 41.0) | 33.5 (25.0, 42.0) |
| Number of follicles ≥11 mmc | 24.0 (16.0, 31.0) | 23.0 (15.0, 28.0) | 23.5 (15.0, 30.0) |
| Number of follicles ≥14 mmc | 17.0 (10.0, 22.0) | 14.0 (11.0, 21.0) | 16.0 (11.0, 21.0) |
| Serum estradiol on day of trigger (pmol/L) | 12 712 (8333, 19 471) | 11 256 (7716, 16 744) | 11 414 (8295, 17 986) |
| Number of patients with serum estradiol on day of trigger ≥11 000 pmol/L (%) | 22 (71.0%) | 24 (77.4%) | 46 (74.1%) |
Contains medians (lower quartile, upper quartile) for continuous variables and numbers of patients (percentages) for categorical variables. Single = patients receiving a single injection of kisspeptin. Double = patients receiving a second injection of kisspeptin 10 h after the first. Both = data for both single and double groups combined.
aAMH = serum anti-Müllerian hormone in pmol/L.
bAnovulation due to polycystic ovarian syndrome.
cOn final ultrasound scan during controlled ovarian stimulation on morning of first kisspeptin-trigger.