Table 1.

Meta-regression Results for the Impact of Selected Variables on the Proportion of Patients Who Were Culture Negative at 8 Weeks

Drug Combinationsa	Covariate: β Regression Coefficient (P Values)
	Year of Publication	Proportion of Patients With HIV Coinfection	Geographical Location (Africa or Not)
HRZE	–0.00 (.27)	0.00 (.79)	0.01 (.87)
HRZ	0.01 (.24)	Insufficient datab	–0.12 (.45)
SHRZ	0.00 (.57)	Insufficient datac	–0.08 (.17)

β coefficients describe how the outcome variable changes with a unit increase in the explanatory variable.

Abbreviation: HIV, human immunodeficiency virus.

^aDrug abbreviations: E, ethambutol; H, isoniazid; R, rifampicin; S, streptomycin; Z, pyrazinamide.

^bOnly 1 study presented proportion of patients with HIV coinfection.

^cNo studies presented proportion of patients with HIV coinfection.