Figure 1.

Prevalence of HIV-1 drug resistance among Ethiopian children experiencing virologic failure of first-line cART. Maximum-likelihood phylogeny inferred from the inclusive consensus sequences of 90 participants for whom genotyping was successful. Drug resistance codons were removed from the alignment prior to phylogenetic inference [48]. Scale indicates expected substitutions per nucleotide site. Colours indicate resistance genotype. Reference strains HXB2 (subtype B, green), MJ4 (subtype C-Botswana, orange) and KU319528 (subtype C-Ethiopia, pink) are included. (Inset) Distribution of HIV-1 resistance genotypes, stratified by drug class.