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Plaque morphology and replication kinetics of wild type and recombinant DEV viruses. (A) Plaque morphology of DEV wild type, DEV-GFP and DEV-HA; (B) the plaque size of DEV wild type, DEV-GFP and DEV-HA; (C) multi-step growth curve of DEV wild type, DEV-GFP and DEV-HA. CEF cells were infected with DEV at MOI 0.01. Viruses were harvested at 6 h, 12 h, 24 h, 48 h and 72 h post-infection. ** p < 0.001.
