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Potency of five selected hit compounds from ion channel library screen.
| Compound | Lab code | PEC50 | Hill slope |
|---|---|---|---|
| DDD00104789 | A | 5.3 | 1.5 |
| DDD00104960 | B | 5.4 | 1.0 |
| DDD00105020 | C | 5.5 | 1.0 |
| DDD00105498 | D | 5.6 | 1.3 |
| DDD00106181 | E | 5.6 | 0.9 |
pEC50 and Hill slopes were determined from concentration effect curves generated for each compound (see also Supplementary Fig. S1).
