Table II.

Adjusted probabilities of implantation, clinical pregnancy and live birth following ART by alcohol and caffeine intake in 300 women (313 unique FFQs, 493 ART cycles) from the EARTH Study.

Categories, range	Number of unique FFQs/cycles	Adjusted proportions (95% CI)a
		Implantation	Clinical pregnancy	Live birth
Alcohol intake, g/day
0.0	32/54	0.53 (0.36–0.69)	0.48 (0.32–0.64)	0.34 (0.20–0.52)
0.1–6.0	127/195	0.66 (0.56–0.75)	0.59 (0.49–0.68)	0.46 (0.36–0.57)
6.1–12.0	63/106	0.66 (0.54–0.76)	0.53 (0.41–0.65)	0.41 (0.29–0.53)
12.1–24.0	72/106	0.62 (0.50–0.74)	0.53 (0.41–0.65)	0.42 (0.31–0.55)
24.1–85.8	19/32	0.62 (0.41–0.80)	0.49 (0.29–0.70)	0.41 (0.22–0.63)
P-trendb		0.95	0.51	0.87
Caffeine intake, mg/day
0.3–50	93/156	0.68 (0.57–0.77)	0.59 (0.48–0.69)	0.46 (0.36–0.57)
50.1–100	48/65	0.69 (0.53–0.81)	0.63 (0.47–0.76)	0.44 (0.29–0.60)
101.1–200	99/151	0.64 (0.53–0.74)	0.52 (0.41–0.62)	0.42 (0.31–0.53)
200.1–300	56/93	0.59 (0.45–0.71)	0.51 (0.39–0.64)	0.40 (0.28–0.53)
300.1–642	17/28	0.52 (0.30–0.73)	0.48 (0.27–0.69)	0.40 (0.21–0.63)
P-trendb		0.08	0.16	0.34

^aData are presented as predictive marginal means adjusted for age, BMI, infertility diagnosis, race, smoking status, alcohol, caffeine, calories, folate and Vitamin B12 intake and dietary patterns, with continuous covariates at their mean level and categorical measures estimated at their reference level.

^bTests for trend were performed using the median level of caffeine and alcohol intake in each group as a continuous variable in the model.