Table IV.

Adjusted mean fertilization rate following ART by alcohol and caffeine intake in 279 women (290 unique FFQs, 389 fresh ART cycles with egg retrieval) from the EARTH Study.

Categories, range	Number of unique FFQs/cycles	Adjusted proportions (95% CI)a
		IVF cycles (n = 181)	ICSI cycles (n = 208)	Combined cycles (n = 389)
Alcohol intake, g/day
0.0	30/38	0.69 (0.55–0.80)	0.64 (0.48–0.77)	0.63 (0.53–0.71)
0.1–6.0	115/151	0.63 (0.55–0.70)	0.77 (0.68–0.84)	0.68 (0.63–0.73)
6.1–12.0	59/83	0.76 (0.67–0.84)	0.74 (0.64–0.82)	0.73 (0.66–0.78)
12.1–24.0	69/91	0.63 (0.54–0.72)	0.77 (0.68–0.84)	0.69 (0.63–0.75)
24.1–85.8	17/26	0.69 (0.51–0.83)	0.79 (0.65–0.89)	0.74 (0.64–0.82)
P-trendb		0.79	0.24	0.18
Caffeine intake, mg/day
0.3–50	88/128	0.67 (0.59–0.75)	0.75 (0.65–0.82)	0.70 (0.64–0.75)
50.1–100	39/47	0.65 (0.52–0.76)	0.66 (0.51–0.78)	0.64 (0.55–0.71)
101.1–200	94/120	0.65 (0.56–0.73)	0.76 (0.67–0.82)	0.69 (0.64–0.74)
200.1–300	53/71	0.68 (0.58–0.77)	0.77 (0.66–0.85)	0.71 (0.64–0.77)
300.1–642	16/23	0.68 (0.47–0.84)	0.84 (0.72–0.92)	0.77 (0.67–0.85)
P-trendb		0.86	0.13	0.23

^aData are presented as predictive marginal means adjusted for age, BMI, infertility diagnosis, race, smoking status, alcohol, caffeine, calories, folate and Vitamin B12 intake and dietary patterns, with continuous covariates at their mean level and categorical measures estimated at their reference level.

^bTests for trend were performed using the median level of caffeine and alcohol intake in each group as a continuous variable in the model.