Fig. 2.
(A) ASR values of certain cancers and average annual temperatures plotted in Earth maps, aside to linear regression plots. (B) Linear regression plots, separately for each gender, for colon cancer and for all cancers. (C) Linear regression plots showing i) the high linearity between average annual temperatures (Celsius degrees) and extreme low temperatures (Celsius degrees) and ii) significant correlation between cancer ASR values and extreme low temperatures. ASR values were plotted by ascending order of eight quartiles (the darker the color the higher the incidence, quartiles can be found in supplementary table S1, Supplementary Material online). Greenland was included in the maps according cancer ASRs reported by Young et al. (2016). Average annual temperatures were plotted according an inverse ascending order (the darker the color the lower the temperature) of eight quartiles. Only countries reported by GLOBOCAN-2012 were included to linear regression analyses. Adjusted R2 is above of each regression plot (both gender included for “all cancers” and “colorectal cancer” plots). Prediction probability is highly significant for all regression analyses.