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. 2017 Dec 5;35(2):473–485. doi: 10.1093/molbev/msx305

Fig. 5.

Fig. 5.

Multiple alignment for TP53 protein for five species. The two critical amino-acid positions contributing to extreme environmental adaptation (Ashur-Fabian et al. 2004; Zhao et al. 2013) are shown with black arrows (lysine-176 for Spalax, asparagine-108, and glutamic acid-108 for Myospalax baileyi and Microtus oeconomus, respectively).