Table 1.

SNPs Mapped from Nonhuman Primates, Neanderthals, and Denisovans to the SRCR Domain of Human MARCO.

Chromosomal Position	Amino Acid Position	Ape Allele	Neanderthal/Denisovan Allele	Human Allele	Ape Amino Acid	Neanderthal/Denisovan Amino Acid	Human Amino Acid
119467242	442	T/C	C	C	I/T	T	T
119467252	445	C	A	A	T	T	T
119467273	452	C/A	A	A	H/Q	Q	Q
119467287	457	C	T	T	T	I	I
119468482	493	C	T	T	S	S	S
119468516	505	T	C	C	H	H	H
119468533	510	T	C	C	H	H	H

Note.—Based on data from the Great Apes Project, common SNPs from Pan troglodytes, Gorilla gorilla, and Pan paniscus to the SRCR domain are shown. Pongo pygmaeus was incomplete and only contained SNPs mapped to the first half of the MARCO gene. For position 452, Nomascus leucogenys was also included, as it was found to have a glutamine residue. Human genome build 18 was used. The MARCO gene is located on chromosome 2 in Humans, Neanderthals, and Denisovan and on chromosome 2B in apes.