Table 2.
Patients With Infection(s) and Time in the ICU
| Pneumonia | UTI (Non-invasive) | Wound | Other | Bacteremia With Sepsis | Total | |
|---|---|---|---|---|---|---|
| Recipient in transmission chain | 2 | 1 | 2 | 0 | 1 | 6 |
| Donor in transmission chain | 3 | 0 | 1 | 0 | 0 | 4 |
| Prior GI colonization | 6 | 1 | 1 | 0 | 0 | 8 |
| Prior throat colonization | 1 | 0 | 0 | 0 | 0 | 1 |
| Unknown source (unique lineage) | 16 (12) | 3 (3) | 4 (1) | 3 (2) | 3 (1) | 29 |
| Total |
28
(5 MDR) |
5 |
8
(4 MDR) |
3 |
4
(2 MDR) |
48 |
Type of infection and source of infection outlined (position/presence in transmission chain, prior colonization, unknown). Note that 3 patients had UTI and bacteremia with sepsis; they are represented here in the bacteremia with sepsis column. “Unknown source” includes those infections for which there is no genetic or epidemiological evidence to indicate whether the infection has arisen from a patient’s own carriage strains or through transmission from another source; numbers in brackets indicate the number of such infections associated with a lineage that was unique to that patient. Note that “unknown source” also includes one patient who had a wound infection diagnosed as K. pneumoniae but genome sequencing found the subcultured isolate to be dominated by A. baumannii DNA; this is consistent with mixed infection or contamination, and prevents reliable comparative analysis with other K. pneumoniae strains.
Abbreviations: GI, gastrointestinal; ICU, intensive care unit; MDR, multidrug-resistant; UTI, urinary tract infection.