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. 2016 Dec 10;64(4):459–467. doi: 10.1093/cid/ciw804

Table 1.

Characteristics of Antiretroviral Therapy–Experienced, HIV-Infected Adults at Study Entry During 2000–2013

Variable HTN
(n = 9547)
No HTN
(n = 58858)
DM
(n = 5881)
No DM
(n = 80908)
CKD
(n = 1785)
No CKD
(n = 50626)
PY = 41291 PY = 323788 PY = 23918 PY = 452258 PY = 10053 PY = 288382
Age, y
 <40 2734 29 27002 46 1488 25 33831 42 430 24 24012 47
 40–49 4201 44 21555 37 2530 43 30270 37 782 44 18553 37
 50–59 2234 23 8673 15 1601 27 13789 17 480 27 7044 14
 60–69 378 4 1628 3 262 4 3018 4 93 5 1017 2
Sex
 Male 8464 89 48908 83 4842 82 67621 84 1481 83 42200 83
Race
 Non-black 4836 51 35330 60 2893 49 47838 59 884 50 28592 56
 Black 4711 49 23528 40 2988 51 33070 41 901 50 22034 44
Injection drug use as HIV transmission risk
 No 6829 72 47617 81 4230 72 63921 79 1191 67 39948 79
Smokinga
 Never 717 8 5927 10 397 7 9153 11 146 8 5653 11
 Ever 2615 27 20798 35 1565 27 30142 37 646 36 19692 39
 Missing 6215 65 32133 55 3919 67 41613 51 993 56 25281 50
BMI, kg/m2
 <18.5 913 10 10268 17 429 7 14001 17 28 2 727 1
 18.5–24.9 685 7 5961 10 408 7 8688 11 284 16 9293 18
 25–29.9 334 3 2184 4 353 6 3401 4 150 8 5655 11
 30–40 58 1 304 1 73 1 473 1 55 3 2391 5
 >40 57 1 851 1 35 1 1102 1 12 1 401 1
 Missing 7500 79 39290 67 4583 78 53243 66 1256 70 32159 64
AIDS
 No 7811 82 47252 80 4668 79 65016 80 1341 75 40770 81
Calendar period of ART initiation
 1996–1999 4651 49 17707 30 2804 48 25534 32 851 48 14895 29
 2000–2005 3669 38 21231 36 2361 40 29892 37 766 43 19204 38
 2006–2013 1101 12 17595 30 638 11 22624 28 138 8 14962 30
CD4 count, cells/µL
 >500 1684 18 10208 17 1257 21 14474 18 284 16 9345 18
 350–499 1219 13 8223 14 852 14 11790 15 197 11 7701 15
 200–349 1772 19 11964 20 1021 17 17167 21 351 20 11118 22
 <200 4870 51 28458 48 2751 47 37471 46 953 53 22459 44
ART and HIV RNA, copies/mL
 ≤400, on ART 2848 30 16091 27 1933 33 23031 28 439 25 14279 28
 >400, on ART 3620 38 26026 44 2202 37 35650 44 853 48 24334 48
 Off ART 207 2 1235 2 187 3 1936 2 60 3 1120 2
 Missing 2872 30 15506 26 1559 27 20291 25 433 24 10893 22

Data are presented as No. (%) unless otherwise indicated. Statistical differences were assessed comparing cases to noncases for each NCD. All covariates were statistically significant (P < .05) with the exception of sex and BMI for the CKD analysis.

Abbreviations: ART, antiretroviral therapy; BMI, body mass index; CKD, chronic kidney disease; DM, diabetes mellitus; HIV, human immunodeficiency virus; HTN, hypertension; NCD, noncommunicable diseases; PY, person-years.

a

Smoking data in NA-ACCORD included observed and imputed observations. Across all 3 study populations, 3% of participants were imputed to be never smokers, 10% were imputed to be ever smokers, 7%–8% were observed as never smokers, 24%–29% were observed as ever smokers, and 50%–56% had missing smoking data. Results of our analyses pooled smoking coefficients across 5 datasets with imputed smoking status, and we obtained valid inferences by accounting for associated covariance matrices between imputed datasets.