Table 2.

Models and Variants Incorporating Different Antifilarial Effects and Different Assumptions on the Transmission Dynamics During the Trial

Model	Permanent Antifilarial Activity	Variant	Assumptions on Short-term and Long-term Changes in Transmission
0	• No macrofilaricidal activity • No sterilizing activity	A	• Constant short-term transmission • Constant long-term transmission
1	• No macrofilaricidal activity • Sterilizing activity	B	• Seasonal short-term transmission • Constant long-term transmission
2	• Macrofilaricidal activity • No sterilizing activity	C	• Constant short-term transmission • Declining long-term transmission
3	• Macrofilaricidal activity • Sterilizing activity	D	• Seasonal short-term transmission • Declining long-term transmission

Nota bene: All variants A to D of models 0 to 3 were fitted to the data separately (ie, 16 separate fits in total).