Figure 4.
Progesterone levels and adverse birth outcomes in efavirenz (EFV) and lopinavir/ritonavir (LPV/r)–treated women. Loge-transformed plasma progesterone in average for gestational age (AGA) and small for gestational age (SGA) outcomes (A and D), average birth weight (ABW) and low birth weight (LBW) deliveries (B and E), and term and preterm (PTB) deliveries (C and F). Data are from women on EFV-based combination antiretroviral therapy (cART) (A–C) and from women on LPV/r-based cART (D–F). All samples analyzed were from women on treatment. Figures depict mean and standard deviations by gestational age category. Statistical significance assessed by 2-way analysis of variance (ANOVA) with Holm posttest. For (D), P = .04 for SGA by 2-way ANOVA. #P = .10 for posttest.