Table 3.

Steps to mitigate shortage of biological supply

Key step	Rationale
Effective management of drug inventory	To minimize interruptions to drug supply
Active management of raw materials	To maintain continuity in manufacturing and a stable drug supply
Maintenance of multi-site manufacturing facilities	To create robustness in manufacturing continuity and thereby address extended supply chain interruptions
Implement robust and secure distribution networks	To ensure supply chain integrity to patients
Implement rapid response to supply interruption signals	To reduce drug shortage risk

Data taken from [92].