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. 2017 Apr 24;56(8):1348–1357. doi: 10.1093/rheumatology/kex072

Table 3.

Causes of deaths in 12 patients with RA-ILD treated with RTX

Patient no. Pattern of ILD FVC pre-RTX DLCO pre-RTX No. of cycles Months since last RTX Cause of death
1 UIP 70 57 4 6 Pneumonia; ILD progression despite CYC and RTX
2 UIP 95 64 3 8 Pneumonia; ILD progression; on home oxygen (LTOT)
3 UIP N/A N/A 3 10 ILD progression
4 UIP 79 57 3 11 ILD progression; on LTOT
5 UIP N/A N/A 3 12 ILD progression
6 UIP N/A 41 2 30 ILD progression despite CYC was added; awaiting lung transplant
7 UIP 72 41 1 36 Pneumonia; ILD progression; on LTOT
8 UIP N/A N/A 2 72 Gastrointestinal bleeding secondary to colon cancer
9 NSIP 111 66 1 6 Infection after neck surgery (atlanto-axial subluxation)
10 NSIP 53 41 1 9 ILD progression; awaiting lung transplant
11 NSIP 103 88 2 12 Metastatic lung cancer
12 NSIP N/A 35 1 15 Pneumonia; ILD progression despite CYC and RTX

LTOT: Long-term oxygen therapy; N/A: Not available.