Table 1.

Genes in the Top 11 Candidate Regions.

Region	Chr	Carrier Haplotype Frequency		P Valuea	Coordinates		Gene Symbol	Gene Name	Location
		CMS	NonCMS		Start	End
1	8	0.12	0.28	5.74E-03	67, 620, 607	68, 221, 368	PTTG3P	Pituitary tumor-transforming 3, pseudogene	8q13.1
							C8orf44	Chromosome 8 open reading frame 44	8q13.1
							SGK3	Serum/glucocorticoid regulated kinase family member 3	8q13.1
							C8orf44-SGK3	C8orf44-SGK3 readthrough	8q13.1
							VCPIP1	Valosin containing protein interacting protein 1	8q13.1
							PPP1R42	Protein phosphatase 1 regulatory subunit 42	8q13.1
							CSPP1	Centrosome and spindle pole associated protein 1	8q13.1-q13.2
							COPS5	COP9 signalosome subunit 5	8q13.1
							TCF24	Transcription factor 24	8q13.1
							SNHG6	small nucleolar RNA host gene 6	8q13.1
							MCMDC2	Minichromosome maintenance domain containing 2	8q13.1
							SNORD87	Small nucleolar RNA, C/D box 87	8q13.1
2	10	0.61	0.78	1.15E-02	47, 618, 434	47, 688, 356	ANTXRL	Anthrax toxin receptor-like	10q11.22
							ANTXRLP1	Anthrax toxin receptor-like pseudogene 1	10q11.22
3	6	0.2	0.36	1.45E-02	106, 358, 412	106, 503, 931	PRDM1	PR/SET domain 1	6q21
4	6	0.89	0.98	2.13E-02	56, 066, 358	56, 150, 981	COL21A1	Collagen type XXI alpha 1 chain	6p12.1
5	3	0.75	0.89	2.34E-02	129, 094, 497	129, 331, 906	MBD4	Methyl-CpG binding domain 4, DNA glycosylase	3q21.3
							IFT122	Intraflagellar transport 122	3q21.3-q22.1
							EFCAB12	EF-hand calcium binding domain 12	3q21.3
							RPL32P3	Ribosomal protein L32 pseudogene 3	3q21.3
							SNORA7B	Small nucleolar RNA, H/ACA box 7B	3q21.3
6	19	0.61	0.76	2.90E-02	22, 811, 834	23, 078, 159	ZNF492	Zinc finger protein 492	19p13.11
							ZNF99	Zinc finger protein 99	19p12
							ZNF723P	Zinc finger protein 723, pseudogene	19p12
7	12	0.73	0.86	3.03E-02	48, 777, 513	48, 886, 484	OR8S1	Olfactory receptor family 8 subfamily S member 1	12q13.2
							C12orf54	Chromosome 12 open reading frame 54	12q13.11
							ANP32D	Acidic nuclear phosphoprotein 32 family member D	12q13.11
							ZNF641	Zinc finger protein 641	12q13.11
8	12	0.81	0.92	3.44E-02	48, 431, 197	48, 529, 882	MIR6505	MicroRNA 6505	12q13.11
							ASB8	Ankyrin repeat and SOCS box containing 8	12q13.11
							SENP1	SUMO1/sentrin specific peptidase 1	12q13.11
							PFKM	Phosphofructokinase, muscle	12q13.11
							COL2A1	Collagen type II alpha 1 chain	12q13.11
							CCDC184	Coiled-coil domain containing 184	12q13.11
9	10	0.8	0.91	4.12E-02	79, 707, 274	79, 893, 495	RPS24	Ribosomal protein S24	10q22.3
							POLR3A	RNA polymerase III subunit A	10q22.3
10	9	0.69	0.82	4.51E-02	17, 053, 836	17, 477, 199	CNTLN	Centlein	9p22.2
11	18	0.15	0.43	2.08E-05	13, 885, 293	13, 918, 846	MC2R	Melanocortin 2 receptor	18p11.2

^aTwo-Tailed Fisher Exact; the start and end position are from genome assembly version GRCh37/hg19.