Fig. 3.

Receiver operating characteristic analysis

Changes in ADC and nADC (i.e. ΔADC and ΔnADC) were used to discriminate responders from non-responders. Separate curves are shown for response classification using clinical and radiological criteria. The optimal operating points are arrowed in blue for nADC and in red for ADC. ADC: apparent diffusion coefficient; nADC: normalized apparent diffusion coefficient; ROC: receiver operating characteristic; ΔADC: change in ADC after therapy; ΔnADC: change in nADC after therapy.