Table 1.
Apparent diffusion coefficient values in radiological responders and non-responders
| Radiological responders | Radiological non- responders | P- values | |
|---|---|---|---|
| ADC pretreatment | 912 (185) | 654 (317) | 0.03 |
| ADC post-treatment | 696 (226) | 962 (296) | 0.16 |
| ΔADC | +240 (407) | −308 (253) | <0.01 |
| nADC pretreatment | 1.67 (0.53) | 1.29 (0.80) | 0.31 |
| nADC post-treatment | 1.42 (0.43) | 1.75 (0.51) | 0.22 |
| ΔnADC | +0.21 (0.27) | −0.25 (0.37) | 0.055 |
Median (interquartile range) nADC, uncorrected ADC, ΔnADC and ΔADC values are shown for responding and non-responding groups. The two groups were compared using the Mann–Whitney-Wilcoxon test; P-values are shown in the right-hand column. Positive ΔnADC and ΔADC values represent an improvement in inflammation; negative values represent a worsening of inflammation. ADC: apparent diffusion coefficient; nADC: normalized apparent diffusion coefficient; ΔADC: change in ADC after therapy; ΔnADC: change in nADC after therapy.