Table 2.
SLE-related medication dispensing prevalence by pregnancy period in women with SLE
| Medication group Medication name | During pregnancya | Pre-pregnancy | Trimester 1 | Trimester 2 | Trimester 3 | Postpartum 1 | Postpartum 2 |
|---|---|---|---|---|---|---|---|
| (%) | (%) | (%) | (%) | (%) | (%) | (%) | |
| DMARDs | 49.3 | 35.4 | 38.9 | 36.7 | 28.6 | 37.1 | 40.4 |
| HCQ | 36.4 | 23.4 | 28.0 | 25.5 | 20.1 | 25.9 | 30.0 |
| AZA | 20.7 | 14.3 | 16.6 | 16.6 | 11.6 | 14.3 | 11.2 |
| Ciclosporin | 1.9 | 1.9 | 1.5 | 1.7 | 1.2 | 1.5 | 1.2 |
| Chloroquine | 1.7 | 2.1 | NA | NA | NA | 1.5 | 1.2 |
| Other DMARDb | NA | 1.7 | NA | NA | NA | 1.7 | 4.4 |
| CSs | 48.0 | 29.8 | 31.5 | 35.8 | 32.5 | 40.0 | 34.2 |
| Prednisolone | 46.2 | 28.2 | 30.4 | 34.4 | 30.6 | 38.1 | 33.1 |
| Betamethasone | 1.7 | 1.5 | NA | NA | 1.2 | 2.1 | NA |
| Other CSc | 1.5 | NA | NA | NA | NA | 1.2 | NA |
| Aspirin | 40.8 | 6.4 | 28.2 | 32.1 | 17.2 | 8.7 | 6.2 |
| Other NSAIDs | 6.0 | 8.5 | 5.0 | NA | NA | 11.0 | 8.1 |
| Diclofenac | 1.9 | 2.7 | NA | NA | NA | 6.8 | 2.5 |
| Naproxen | 1.7 | 2.1 | 1.7 | NA | 0 | 1.2 | 2.7 |
| NSAIDs excluding aspirin, diclofenac and naproxend | 2.5 | 4.4 | 2.3 | NA | 0 | 3.1 | 3.3 |
a
During pregnancy includes trimesters 1, 2 and 3.
b
Includes the following medications with n ≤ 5 during pregnancy: SSZ, mycophenolic acid, etanercept and MTX.
c
Includes the following medications with n ≤ 5 during pregnancy: methylprednisolone, prednisone and dexamethasone.
d
Includes the following medications with n ≤ 5 during pregnancy: ibuprofen, ketoprofen, dexibuprofen, celecoxib, etoricoxib and nabumetone. NA: there are five or fewer individuals.