Table 2.
Common DEGs among the HRpEF animal models
| Animal models | Gene names | Entrez Gene Name | Location | Type |
| Dahl/SS and SHHF | ADRA1D | Adrenoceptor alpha 1D | Plasma Membrane | G-protein coupled receptor |
| AKIP1 | A-kinase interacting protein 1 | Nucleus | Other | |
| ALOX15 | Arachidonate 15-lipoxygenase | Cytoplasm | Enzyme | |
| ANKRD23 | Ankyrin repeat domain 23 | Nucleus | Other | |
| APLN | Apelin | Extracellular Space | Other | |
| Bex1/LOC100912195 | Brain expressed, X-linked 1 | Cytoplasm | Other | |
| CDC25B | Cell division cycle 25B | Nucleus | Phosphatase | |
| COL8A1 | Collagen type VIII alpha 1 chain | Extracellular Space | Other | |
| EPN3 | Epsin 3 | Cytoplasm | Other | |
| FHL1 | Four and a half LIM domains 1 | Cytoplasm | Other | |
| FIBIN | Fin bud initiation factor homolog (zebrafish) | Cytoplasm | Other | |
| FXYD3 | FXYD domain containing ion transport regulator 3 | Plasma Membrane | Other | |
| Hamp | Hepcidin antimicrobial peptide | Extracellular Space | Other | |
| MS4A6A | Membrane spanning 4-domains A6A | Other | Other | |
| MYH6 | Myosin heavy chain 6 | Cytoplasm | Enzyme | |
| MYH7 | Myosin heavy chain 7 | Cytoplasm | Enzyme | |
| NPPA | Natriuretic peptide A | Extracellular Space | Other | |
| NUPR1 | Nuclear protein 1, transcriptional regulator | Nucleus | Transcription regulator | |
| SFRP1 | Secreted frizzled related protein 1 | Plasma Membrane | Transmembrane receptor | |
| TRDN | Triadin | Cytoplasm | Other | |
| Diabetes 1 and SHHF | COL4A1 | Collagen type IV alpha 1 chain | Extracellular Space | Other |
| COL6A1 | Collagen type VI alpha 1 chain | Extracellular Space | Other | |
| CREG1 | Cellular repressor of E1A stimulated genes 1 | Nucleus | Transcription regulator | |
| CXCL3 | Chemokine (C-X-C motif) ligand 3 | Extracellular Space | Cytokine | |
| ELK3 | ELK3, ETS transcription factor | Nucleus | Transcription regulator | |
| FAM49B | Family with sequence similarity 49 member B | Extracellular Space | Other | |
| KANK2 | KN motif and ankyrin repeat domains 2 | Nucleus | Transcription regulator | |
| KLF9 | Kruppel like factor 9 | Nucleus | Transcription regulator | |
| PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1 | Cytoplasm | Other | |
| PLXND1 | Plexin D1 | Plasma Membrane | Transmembrane receptor | |
| PTP4A2 | Protein tyrosine phosphatase type IVA, member 2 | Cytoplasm | Phosphatase | |
| PTPN3 | Protein tyrosine phosphatase, non-receptor type 3 | Cytoplasm | Phosphatase | |
| SIPA1L1 | Signal induced proliferation associated 1 like 1 | Cytoplasm | Other | |
| WDR45 | WD repeat domain 45 | Other | Other | |
| ZFP532 | Zinc finger protein 532 | Nucleus | Other |