Fig. 1.

Estimates of dN, dS, and $\frac{\mathrm{d}N}{\mathrm{d}S}$ with a stationary model (left) and with a nonstationary model (right), on simulated data with changing G + C content and $\omega =0.1$. θ_root: G + C frequency in the root sequence. θ_eq: G + C equilibrium frequency of the simulation model.