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. 2018 Feb 28;2018:5179468. doi: 10.1155/2018/5179468

Figure 2.

Figure 2

Inhibition of TRPA1 ameliorates cardiac function in mice treated with Dox. (a, b) The body weight (BW) and heart weight (HW) in different groups (n = 10). (c, d) The serum levels of cardiotoxicity markers, including creatine kinase isoenzymes (CK-MB) and lactate dehydrogenase (LDH) (n = 6). (e, f) The echocardiographic parameters in different groups (n = 8). (g) The pathological structure indicated by HE staining (scale bar, 50 μm) (n = 6). ∗P < 0.05 compared with the CTRL group. #P < 0.05 compared with the Dox group. EF: ejection fraction; FS: fractional shortening.