Table 2.
Expression analysis of Smurf2, CNKSR2, ER, PR and HER2 in non-malignant and malignant breast tissue samples
| Grade of Tumour | |||||
|---|---|---|---|---|---|
| Proteins studied | Staining intensity | Non-Malignant (n = 22) | Malignant (n = 62) | Total (n = 84) | P-Value |
| Smurf2 | No/Mild | 16(72.73%) | 6(9.68%) | 22(26.19%) | P < 0.001 |
| Moderate/Intense | 6(27.27%) | 56(90.32%) | 62(73.81%) | ||
| CNKSR2 | No/Mild | 17(77.27%) | 8(12.90%) | 25(29.76%) | P < 0.001 |
| Moderate/Intense | 5(22.73%) | 54(87.10%) | 59(70.24%) | ||
| ER | No/Mild | 16(72.73%) | 44(70.97%) | 60(71.43%) | P = 0.875 |
| Moderate/Intense | 6(27.27%) | 18(29.03%) | 24(28.57%) | ||
| PR | No/Mild | 10(45.45%) | 45(72.58%) | 55(65.48%) | P < 0.05 |
| Moderate/Intense | 12(54.55%) | 17(27.42%) | 29(34.52%) | ||
| HER2 | No/Mild | 16(72.73%) | 27(43.55%) | 43(51.19%) | P < 0.05 |
| Moderate/Intense | 6(27.27%) | 35(56.45%) | 41(48.81%) | ||