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. 2018 Mar 13;49:30. doi: 10.1186/s13567-018-0524-z

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of IFNa, IFNc and Mx genes in spleen during PRV infection and effect of IHNV co-challenge. Fold increase in gene expression of interferon (IFN)a (A), IFNc (B) and the IFN− regulated antiviral gene Mx (C) in spleen during the course of infection with PRV in Atlantic salmon cohabitants from tank 4 (PRV+/IHNV+) and tank 5 (PRV+/IHNV−). Gene expression is normalized to the reference gene EF1α, and shown as fold induction compared to uninfected controls from tank 6 (PRV−/IHNV−).