Fig. 4.
Older synm −/− mice show an increase in body weight and heart size compared to controls. Intact hearts of 13 month-old synm −/− and WT mice (A). Frozen cross sections of synm −/− and WT heart stained with hematoxylin and eosin (2×) (B). Body weight (BW) (C), and body and heart weight (HW) normalized to tibia length (TL) (D and E). *p < 0.05, n = 12; Scale bar = 1 mm.