Table 1.
Relationships between PNI and clinicopathological features in overall gastric cancer patients before and after propensity score matching
| All patients | Propensity matched patients | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | Total patients | PNI | Total patients | PNI | ||||
| < 44.3 | ≥44.3 | < 44.3 | ≥ 44.3 | |||||
| (n = 109) | (n = 259) | p value | (n = 109) | (n = 109) | p value | |||
| Age (years) | 75.8 ± 9.2 | 68.5 ± 11.2 | < 0.001 | 75.8 ± 9.2 | 68.3 ± 11.0 | < 0.001 | ||
| Sex | 0.124 | 0.315 | ||||||
| Male | 254 | 69 | 185 | 145 | 69 | 76 | ||
| Female | 114 | 40 | 74 | 73 | 40 | 33 | ||
| BMI | 21.45 ± 3.42 | 22.85 ± 3.41 | < 0.001 | 21.45 ± 3.42 | 22.61 ± 3.13 | 0.009 | ||
| WBC (μl) | 5416.8 ± 1464.3 | 5877.0 ± 1342.9 | 0.004 | 5416.8 ± 1464.3 | 6050.1 ± 1407.6 | 0.001 | ||
| RBC (× 104 μl) | 365.8 ± 55.9 | 465.1 ± 356.3 | 0.004 | 365.8 ± 55.9 | 470.4 ± 432.3 | 0.013 | ||
| Location of tumor | 0.187 | 0.333 | ||||||
| EGJ | 11 | 2 | 9 | 6 | 2 | 4 | ||
| U | 70 | 23 | 47 | 41 | 23 | 18 | ||
| M | 162 | 40 | 122 | 91 | 40 | 51 | ||
| L | 125 | 44 | 81 | 80 | 44 | 36 | ||
| Tumor size (mm) | 60.37 ± 33.40 | 41.89 ± 28.74 | < 0.001 | 60.37 ± 33.40 | 48.06 ± 32.05 | < 0.006 | ||
| Procedure | 0.090 | 0.954 | ||||||
| LTG | 82 | 31 | 51 | 60 | 31 | 29 | ||
| LPG | 37 | 7 | 30 | 14 | 7 | 7 | ||
| L(A)DG | 249 | 71 | 178 | 144 | 71 | 73 | ||
| Differentiation | 0.123 | 0.919 | ||||||
| Well | 71 | 14 | 57 | 27 | 14 | 13 | ||
| Moderate | 134 | 42 | 92 | 82 | 42 | 40 | ||
| Poor | 163 | 53 | 110 | 109 | 53 | 56 | ||
| Depth of tumor | < 0.001 | 0.937 | ||||||
| T1a-1b | 190 | 40 | 150 | 80 | 40 | 40 | ||
| 2 | 48 | 12 | 36 | 27 | 12 | 15 | ||
| 3 | 54 | 23 | 31 | 45 | 23 | 22 | ||
| 4a-4b | 74 | 34 | 40 | 66 | 34 | 32 | ||
| Lymph node metastasis | 0.010 | 0.813 | ||||||
| N0 | 244 | 59 | 185 | 120 | 59 | 61 | ||
| N1 | 40 | 14 | 26 | 30 | 14 | 16 | ||
| N2 | 42 | 19 | 23 | 33 | 19 | 14 | ||
| N3 | 42 | 17 | 25 | 35 | 17 | 18 | ||
| Pathological stage | < 0.001 | 0.963 | ||||||
| 1a-1b | 217 | 45 | 172 | 92 | 45 | 47 | ||
| 2a-2b | 65 | 26 | 39 | 51 | 26 | 25 | ||
| 3a-3c | 86 | 38 | 48 | 75 | 38 | 37 | ||
| Operation time (min) | 416.1 ± 126.0 | 419.5 ± 116.3 | 0.804 | 416.1 ± 126.0 | 430.5 ± 121.2 | 0.391 | ||
| Intraoperative | ||||||||
| blood loss (ml) | 325.3 ± 699.0 | 180.8 ± 359.9 | 0.009 | 325.3 ± 699.0 | 257.0 ± 485.4 | 0.404 | ||
| Albumin (g/dl) | 3.26 ± 0.49 | 4.21 ± 0.34 | < 0.001 | 3.26 ± 0.49 | 4.20 ± 0.35 | < 0.001 | ||
| CRP (mg/l) | 0.705 ± 1.22 | 0.190 ± 0.540 | < 0.001 | 0.705 ± 1.22 | 0.205 ± 0.478 | < 0.001 | ||
| CEA (ng/ml) | 0.117 | 0.204 | ||||||
| < 5 | 286 | 79 | 207 | 166 | 79 | 87 | ||
| > 5 | 82 | 30 | 52 | 52 | 30 | 22 | ||
| Adjuvant chemotherapy | 0.541 | 0.035 | ||||||
| Yes | 100 | 32 | 68 | 79 | 32 | 47 | ||
| No | 268 | 77 | 191 | 139 | 77 | 62 | ||