Table 1.
Basic clinical data and kidney function parameters depending on thrombomodulin concertation in the investigated group of 59 patients.
| Parameter | Thrombomodulin | p value∗ | |
|---|---|---|---|
| <2xULN (n = 26) | ≥2xULN (n = 33) | ||
| Age (years) | 10.5 (5.0; 16.0) | 12.1 (9.1; 15.3) | 0.277 |
| Male sex (n) | 17 (65.4%) | 19 (57.5%) | 0.599 |
| Height (z-score) | −0.35 (−1.77; 0.07) | −1.34 (−2.38; −0.27) | 0.097 |
| Body mass (z-score) | −0.84 (1.30; 0.11) | −1.06 (−2.55; −0.01) | 0.320 |
| BMI (kg/m2) | 16.5 (15.8; 18.6) | 16.8 (14.9; 20.1) | 0.970 |
| BMI (z-score) | −0.62 (−1.11; 0.53) | −0.66 (−1.45; 0.44) | 0.903 |
| Creatinine (μmol/l) | 110.8 (93.8; 179.3) | 403.0 (283.3; 725.3) | <0.001 |
| Cystatin (mg/l) | 1.58 (1.25; 2.06) | 4.21 (3.05; 5.82) | <0.001 |
| eGFR Filler (ml/min/1.73 m2) | 55.2 (38.8; 72.0) | 18.4 (12.0; 26.2) | <0.001 |
| Microalbuminuria (mg/l) | 18.0 (10,7; 63.0) | 99.5 (24.5; 423.0) | 0.005 |
Values presented as median (25th–75th percentile). ∗Mann–Whitney U test. ULN: upper limit of normal; BMI: body mass index; eGFR: estimated glomerular filtration rate.