Table 2.
Number | Metabolites | RT (min) | VIP value | p value | Fold change | Variations versus healthy controls |
---|---|---|---|---|---|---|
1 | 3-Phosphoglycerate | 12.552 | 2.356 | 0.001 | 6.901 | ↓ |
2 | Lactic acid | 13.986 | 2.104 | 0.001 | 1.904 | ↓ |
3 | Tryptophan | 22.841 | 2.094 | 0.002 | 6.051 | ↓ |
4 | 2-Amino-1-phenylethanol | 8.318 | 2.095 | 0.002 | 3.196 | ↓ |
5 | 5-Aminovaleric acid | 23.320 | 2.125 | 0.002 | 2.847 | ↓ |
6 | Dithioerythritol | 13.233 | 1.912 | 0.002 | 0.135 | ↑ |
7 | Glutamic acid | 9.391 | 1.628 | 0.002 | 1.522 | ↓ |
8 | 8-Aminocaprylic acid | 18.527 | 2.106 | 0.002 | 1.847 | ↓ |
9 | Phytosphingosine | 8.151 | 2.119 | 0.003 | 8.511 | ↓ |
10 | Guanosine | 24.600 | 1.707 | 0.004 | 9.838 | ↓ |
11 | 6-Methylmercaptopurine | 11.717 | 1.824 | 0.004 | 7.725 | ↓ |
12 | Norvaline | 11.161 | 1.935 | 0.005 | 2.686 | ↓ |
13 | Leucine | 5.815 | 1.666 | 0.007 | 2.123 | ↓ |
14 | cis-Gondoic acid | 22.021 | 1.558 | 0.007 | 2.426 | ↓ |
15 | Zymosterol | 29.154 | 3.483 | 0.008 | 0.260 | ↑ |
16 | Methyl heptadecanoate | 9.303 | 1.651 | 0.014 | 3.480 | ↓ |
17 | Pipecolinic acid | 12.805 | 1.691 | 0.015 | 2.762 | ↓ |
18 | Orotic acid | 11.033 | 1.643 | 0.015 | 0.070 | ↑ |
19 | 2-Deoxyerythritol | 10.399 | 1.391 | 0.015 | 0.067 | ↑ |
20 | Phenylethylamine | 14.907 | 1.626 | 0.016 | 11.745 | ↓ |
21 | Guanidinosuccinic acid | 9.656 | 1.496 | 0.017 | 1.325 | ↓ |
22 | trans-4-Hydroxy-L-proline | 7.807 | 1.664 | 0.017 | 10.533 | ↓ |
23 | D-Glyceric acid | 6.459 | 1.571 | 0.018 | 4.052 | ↓ |
24 | Benzoic acid | 5.602 | 1.426 | 0.019 | 0.380 | ↑ |
25 | alpha-Tocopherol | 28.449 | 1.700 | 0.021 | 6.013 | ↓ |
26 | N-(3-aminopropyl)-morpholine | 10.587 | 1.794 | 0.021 | 3.753 | ↓ |
27 | Picolinic acid | 6.470 | 1.405 | 0.022 | 1.394 | ↓ |
28 | DL-dihydrosphingosine | 20.104 | 1.206 | 0.025 | 1.405 | ↓ |
29 | 2-Aminoethanethiol | 12.512 | 1.454 | 0.028 | 1.508 | ↓ |
30 | Cysteine | 9.222 | 1.404 | 0.034 | 3.934 | ↓ |
31 | Cytidine | 25.557 | 1.215 | 0.036 | 2.384 | ↓ |
32 | Ethanolamine | 16.080 | 1.482 | 0.042 | 0.838 | ↑ |
33 | Monoolein | 24.574 | 1.502 | 0.047 | 5.496 | ↓ |