. 2018 Feb 26;113(5):e170467. doi: 10.1590/0074-02760170467

TABLE II. Sensitivity and specificity of the evaluated antigens in the serodiagnosis of multibacillary leprosy.

Antigens	Isotypes	Cutoff^a	Sensitivity^b	Specificity^b	+LR^c	-LR^c
NDO-HSA	IgM	16.93	70	98	35.0	0.31
	IgG	5.25	85	78	3.86	0.19
	IgG1	1.31	75	88	6.25	0.28
	IgG2	1.56	65	78	2.95	0.45
	IgG3	1.82	70	84	4.37	0.36
LID-1	IgM	6.06	80	82	4.44	0.24
	IgG	40.26	90	100	48.0	0.10
	IgG1	18.10	90	100	11.0	0.10
	IgG2	2.49	80	88	6.67	0.23
	IgG3	6.13	85	74	3.27	0.20
NDO-LID	IgM	18.02	85	86	6.07	0.17
	IgG	39.28	95	98	47.5	0.05
	IgG1	5.15	90	90	9.00	0.11
	IgG2	2.36	85	82	4.72	0.18
	IgG3	5.14	90	88	7.50	0.11

a: cutoff, sensitivity and specificity data were determined based on the analysis of receiver operating characteristic (ROC) curves; b: the values of sensitivity and specificity were determined according to the point of the ROC curve nearest to the point of sensitivity and specificity equal to 100%; c: +LR and -LR = positive and negative likelihood ratio (LR).