Table 1. Correlation analysis of DHRS2 downregulation with clinicopathologic characteristics of ESCC patients.
Clinicopathologic characteristics | DHRS2 downregulation | P-value |
---|---|---|
Age (years) | 0.836 | |
<60 | 29/92 (31.52%) | |
>=60 | 28/93 (30.11%) | |
Gender | 0.911 | |
Male | 32/105 (30.48%) | |
Female | 25/80 (31.25%) | |
Tumor cell differetiation | 0.703 | |
Well | 6/25 (24.00%) | |
Moderate | 40/114 (35.09%) | |
Poor | 11/46 (23.91%) | |
Tumor invasion | <0.001 | |
0–1 | 10/74 (13.51%) | |
2 | 3/10 (30.00%) | |
3 | 44/101 (43.56%) | |
Lymph node metastasis | <0.001 | |
− | 30/131 (22.90%) | |
+ | 27/54 (50.00%) | |
Staging | <0.001 | |
0, I | 9/74 (12.16%) | |
II, III, IV | 48/111 (43.24%) |
Abbreviations: DHRS2, short-chain dehydrogenase/reductase family, member 2; ESCC, eesophageal squamous cell carcinoma. Bold values indicate statistically significant.