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. 2017 Feb 24;38(3):422–432. doi: 10.1177/0271678X17694905

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Figure 2. — Box-whisker plots (whiskers: minimum, maximum; box: 25th to 75th percentile; line: mean value) VTH mapping parameters and the PO2_mit values of all patients with newly-diagnosed glioblastoma (N = 25) and recurrent glioblastoma (N = 32). (a) macrovascular and microvascular VTH (MVTH and µVTH) within newly-diagnosed (left part) and recurrent glioblastoma (right part). µVTH was significant higher (P = 0.014) in recurrent glioblastoma compared to newly-diagnosed glioblastoma. (b) macrovascular and microvascular MTT (MMTT and µMTT) within newly-diagnosed (left part) and recurrent glioblastoma (right part). MMTT was increased in recurrent glioblastoma but reached not statistical significance. (c) macrovascular and microvascular COV (MCOV and µCOV) within newly-diagnosed (left part) and recurrent glioblastoma (right part). µCOV was significant higher (P = 0.039) in recurrent glioblastoma compared to newly-diagnosed glioblastoma. (d) oxygen tension in tissue surrounding mitochondria (PO2_mit) within newly-diagnosed (left part) and recurrent glioblastoma (right part). PO2_mit was significant lower (P = 0.008) in recurrent glioblastoma compared to newly-diagnosed glioblastoma. Macrov: macrovasculature; microv: microvasculature.