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. 2018 Mar 13;17:47. doi: 10.1186/s12944-018-0687-7

Fig. 2.

Fig. 2

SERCA activity in sham and overloaded (OVL) plantaris muscles. (a) Representative SERCA activity-pCa curves. (b) Maximal SERCA activity is reduced in the overloaded plantaris. (c) SERCA’s apparent affinity for calcium is unaltered in the overloaded plantaris compared with sham. *Significantly different from sham, p ≤ 0.05; (n = 6 per group). pCa50 is the negative logarithm of [Ca2+] required to elicit half maximal SERCA activity