Table 1.
Overview of patients with medication-related osteonecrosis of the jaws (MR-ONJ) and the control-group.
| Values | Control Group | MR-ONJ | p-Value |
|---|---|---|---|
| n | 1339 | 35 | |
| Age mean | 47.53 | 64.94 | p < 0.001 |
| Age min | 0 | 45 | |
| Age Max | 99 | 88 | |
| Age standard deviation | 23.85 | 8.37 | |
| Known diabetes (%) | 115 (8.6) | 5 (14.3) | p = 0.223 |
| Diabetes therapy | |||
| Dietary (%) | 31 (27.0) | 0 | |
| Medicinal (%) | 84 (73.0) | 5 (100.00) | |
| Nephropathy (%) | 33 (28.7) | 3 (60.0) | |
| Increased Creatinine level (%) | 14 (12.1) | 0 | |
| Neuropathy | 17 (14.8) | 0 | |
| Retinopathy | 5 (4.3) | 1 (20.0) | |
| Diabetic foot ulcer | 4 (3.5) | 0 | |
| Gangrene | 1 (0.9) | 0 | |
| Metformin | 29 (25.2) | 2 (40.0) | |
| Glinide | 0 | 0 | |
| Acarbose | 0 | 0 | |
| Sulfonylurea | 14 (12.1) | 1 (20.0) | |
| Glitazone | 0 | 0 | |
| Gliptin | 4 (3.5) | 0 | |
| Insulin | 38 (33.0) | 2 (40.0) | |
| Average maximum blood glucose level (mg/dL) | 105 | 113 | |
| Number of patients with glucose values above 200 mg/dL (%) | 142 (11.4) | 10 (28.5) | p < 0.001 |
| Number of diabetics (%) | 80 (56.3) | 4 (40) |