Table 3.
Association of famine exposure with eGFR and chronic kidney diseases using an equation especially for Asian
| Fetal-exposed (1959–1962) | Childhood-exposed (1949–1958) | Adolescence/adult-exposed (1921–1948) | Non-exposed (1963–1974) | |
|---|---|---|---|---|
| eGFR | ||||
| Model 1 | −1.39(−2.81, 0.03) | −0.05(−1.84, 1.75) | −0.13(−3.03, 2.78) | Ref. |
| Model 2 | −1.45(−2.83, −0.07)* | 0.32(−1.43, 2.07) | 1.01(−1.82, 3.84) | Ref. |
| Model 3 | −1.42(−2.80, −0.04)* | 0.31(−1.45, 2.06) | 0.94(−1.89, 3.76) | Ref. |
| CKD | ||||
| Model 1 | 3.99(1.25, 12.74)* | 2.43(0.77, 7.73) | 2.90(0.72, 11.78) | Ref. |
| Model 2 | 3.91(1.22, 12.49)* | 2.20(0.69, 7.07) | 2.29(0.56, 9.47) | Ref. |
| Model 3 | 3.73(1.16, 11.94)* | 2.03(0.63, 6.55) | 2.06(0.50, 8.59) | Ref. |
Data are expressed as unstandardized coefficients (95%CI) in eGFR and odds ratios (95%CI) in chronic kidney disease. Linear regression analyses were used. eGFR, estimated glomerular filtration rate; CKD, chronic kidney diseases. CKD was defined as eGFR less than 60 mL/min per 1.73 m2
For a woman with Scr ≤ 0.7 mg/dl, eGFR = 151 × (Scr/0.7)−0.328 × (0.993)age; for a woman with Scr > 0.7 mg/dl, eGFR = 151 × (Scr/0.7)−1.210 × (0.993)age
Model 1 included age; Model 2 included age, rural/urban residence, economic status of areas; Model 3 included terms for model 2, BMI, diabetes and systolic blood pressure
* indicated P < 0.05.