Table 2.

Plasma levels of lipid species before and after very low calorie diet

	Before VLCD	After VLCD	p value
N-acylethanolamines (pmol/mL)
AEA	0.94 ± 0.41	0.82 ± 0.30	0.024
PEA	7.57 ± 2.03	6.26 ± 1.28	<0.001
SEA	6.36 ± 1.79	4.88 ± 0.87	<0.001
POEA	0.55 ± 0.47	0.34 ± 0.24	0.003
OEA	5.13 ± 1.57	4.74 ± 1.17	0.091
LEA	2.52 ± 0.64	2.13 ± 0.38	0.001
Alpha-LEA	0.19 ± 0.06	0.15 ± 0.03	0.003
DGLEA	0.16 ± 0.08	0.12 ± 0.04	<0.001
PDEA	0.09 ± 0.03	0.08 ± 0.02	0.105
EPEA	0.60 ± 0.37	0.37 ± 0.24	0.001
DEA	0.28 ± 0.08	0.25 ± 0.07	0.009
DHEA	5.51 ± 2.16	4.21 ± 2.04	<0.001
Monoacylglycerols (pmol/mL)
2-AG	2.63 ± 1.25	2.42 ± 0.82	0.355
1-OG	425 ± 35	423 ± 38	0.828
2-OG	75 ± 30	68 ± 18	0.189
1-LG	79 ± 19	76 ± 14	0.378
2-LG	24 ± 11	21 ± 8	0.279

Data are mean ± SD, n = 27. p value before vs. after VLCD based on a paired sample t-test

1-LG 1-linoleoyl glycerol, 1-OG 1-oleoyl glycerol, 2-AG 2-arachidonoyl glycerol, 2-LG 2-linoleoyl glycerol, 2-OG 2-oleoyl glycerol, AEA anandamide, Alpha-LEA N-α-linolenylethanolamide, DEA N-docosatetraenoylethanolamide, DGLEA dihomo-γ-linolenoyl ethanolamide, DHEA N-docosahexaenoylethanolamide, EPEA eicosapentaenoyl ethanolamide, LEA: N-linoleoylethanolamide, OEA N-oleoylethanolamide, PDEA N-pentadecanoylethanolamide, PEA N-palmitoylethanolamide, POEA N-palmitoleoylethanolamide, SEA N-stearoylethanolamide