Table 2. Eleven SNPs tested in the validation and combined datasets.

SNP	Gene	Quality	RegulomeDB	MAF	Discovery		Validation		Combined
(chromosome)		scorea	scoreb		N (Dead|Alive)	MSTd	N (Dead|Alive)	MST	N (Dead|Alive)	MST
rs113988120 (2)	PAIP2B	0.9	6	0.015
TT					721|118	14.9	505|248	19.7	1226|366	16.3
TA					29|0	9.7	20|5	14.7	49|5	10.3
AA					0|0	-	4|1	13.3	4|1	13.7
rs4780973 (16)	LOC101927026	0.99	5	0.31
CC					377|53	12.9	267|109	17.6	644|162	14.7
CT					315|50	15.07	228|119	17.6	543|169	16.2
TT					58|15	21.7	44|27	22.4	102|42	21.93
rs9815265 (2)	RAB6B	0.9	3	0.403
TT					279|36	13.4	165|86	19.5	444|122	14.8
TC					362|55	14.6	264|108	19.1	626|163	15.6
CC					109|27	22	126|65	18.7	235|92	18.8
rs6438217 (3)	ZBTB20	1	6	0.164
TT					492|93	15.7	367|173	19.5	859|266	16.6
TC					234|22	13.9	166|80	19.5	400|102	14.8
CC					24|3	10.5	19|5	13.3	43|8	12.4
rs12638565 (3)	ROBO1	0.93	No data	0.233
CC					448|72	16	310|143	20.7	758|215	17.3
CT					264|43	13.1	180|87	17.6	444|130	14.4
TT					38|3	9.5	60|27	19.7	98|30	13.7
rs4568126 (3)	B4GALT4	0.99	6	0.421
CC					266|35	13.4	120|59	18.4	386|94	14.5
CA					361|53	14.3	249|123	18.8	610|176	15.4
AA					123|30	18.6	187|77	20	310|107	18.9
rs12186112 (3)	UPK1B	0.99	6	0.405
AA					286|40	12.9	199|82	19.5	485|122	14.7
AC					342|52	14.8	250|122	19.5	592|174	16.3
CC					122|26	18.3	93|49	18.1	215|75	17.4
rs13060627 (3)	LRRC15	1	V264I	0.264
CC					423|58	13.1	304|144	19	727|202	14.7
CT					281|46	15.7	207|95	20.3	488|141	17.2
TT					46|14	20	37|18	15	83|32	18.4
rs923936 (3)	LRRC15	1	L133L	0.234
GG					458|62	13.5	29|13	18.5	487|75	13.8
GA					254|43	15.2	203|92	19.5	457|135	16.9
AA					38|13	20.7	313|150	19	351|163	17.6
rs13173842 (5)	SLIT3	0.79	4	0.321
CC					363|59	15.1	246|116	18.9	609|175	16
CT					305|52	14.8	237|112	20.1	542|164	16.3
TT					82|7	12.4	60|27	17.3	142|34	13.7
rs10926274 (1)	NA	0.72	4	0.483
AA					189|22	12.4	127|50	19.1	316|72	14.2
AG					393|57	14.8	262|131	19.9	655|188	15.8
GG					168|39	17	162|72	18.4	330|111	17

^aImputation quality score.

^bMinor allele frequency based on imputation of the GWAS data.

^cScore 3a, 4,5, and 6 indicate TF binding + any motif + DNase peak, TF binding + DNase peak, TF binding or DNase peak, or other, respectively.

^dMedian survival time in months.