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. Author manuscript; available in PMC: 2018 Mar 14.
Published in final edited form as: Nat Rev Rheumatol. 2016 Mar 24;12(5):259–268. doi: 10.1038/nrrheum.2015.179

Figure 1. Activated macrophages in bone marrow inflammatory infiltrate in MAS.

Figure 1

a | Myelocyte within an activated macrophage. In addition, there are multiple adherent red blood cell and myeloid precursors. b | Activated macrophage engulfing a band neutrophil. c | Band neutrophil and metamyelocyte within an activated macrophage. Nuclei of neutrophil band appear condensed. d | Activated macrophage with haemosiderin deposits and a degenerating phagocytosed nucleated cell. H&E stain, original magnification ×1000. MAS, macrophage activation syndrome. Reproduced with permission from Prahalad, S. et al. Etanercept in the treatment of macrophage activation syndrome. J. Rheumatol. 28, 2120–2124 (2001). All rights reserved.