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. Author manuscript; available in PMC: 2018 Mar 14.
Published in final edited form as: Nat Rev Rheumatol. 2016 Mar 24;12(5):259–268. doi: 10.1038/nrrheum.2015.179

Figure 2. T cells in bone marrow inflammatory infiltrate in MAS.

Figure 2

Immunohistochemical assessment of the T lymphocyte infiltrate in a bone marrow biopsy from a patient with macrophage activation syndrome (MAS) presenting as a complication of systemic juvenile idiopathic arthritis (sJIA). a | Immunohistochemical staining with anti-CD8 antibodies shows numerous CD8+ T lymphocytes; b | CD4 staining shows only rare CD4+ T lymphocytes.