Table 2. ROC curve AUC score with 95% confidence intervals.

Score	Test I	Test II
CADD	0.85 (0.79–0.90)	0.78 (0.78–0.79)
DANN	0.84 (0.79–0.89)	0.75 (0.74–0.75)
Eigen	0.86 (0.81–0.91)	0.67 (0.66–0.68)
FATHMM	0.84 (0.78–0.89)	0.91 (0.90–0.91)
GERP++	0.79 (0.73–0.84)	0.68 (0.67–0.68)
LRT	0.85 (0.80–0.90)	0.73 (0.72–0.74)
MLP	0.90 (0.86–0.94)	0.94 (0.94–0.95)
MetaLR	0.90 (0.86–0.94)	0.93 (0.93–0.94)
MetaSVM	0.90 (0.86–0.94)	0.92 (0.92–0.93)
MutationAssessor	0.78 (0.71–0.83)	0.77 (0.77–0.78)
MutationTaster	0.91 (0.87–0.94)	0.76 (0.75–0.77)
PROVEAN	0.82 (0.77–0.88)	0.77 (0.77–0.78)
PolyPhen HDIV	0.79 (0.73–0.85)	0.77 (0.76–0.77)
PolyPhen HVAR	0.80 (0.74–0.86)	0.79 (0.78–0.79)
SIFT	0.77 (0.71–0.82)	0.78 (0.77–0.78)
SiPhy 29-way	0.82 (0.76–0.87)	0.70 (0.70–0.71)
phastCons 100-way	0.81 (0.76–0.86)	0.69 (0.69–0.70)
phyloP 100-way	0.89 (0.85–0.93)	0.75 (0.74–0.76)
sdAE	0.92 (0.88–0.95)	0.92 (0.92–0.93)