Table 6. MLP’s and sdAE’s average precision with 95% confidence intervals evaluated on subsets of SNVs from the training dataset II that could not be processed by other predictors.
Score | Number predictions | MLP | sdAE |
---|---|---|---|
Eigen | 1175 | 1.00 (0.99–1.00) | 0.99 (0.99–1.00) |
FATHMM | 898 | 0.52 (0.42–0.62) | 0.18 (0.11–0.25) |
LRT | 1772 | 0.83 (0.79–0.87) | 0.74 (0.69–0.78) |
MetaLR | 118 | 0.81 (0.70–0.90) | 0.63 (0.51–0.75) |
MetaSVM | 118 | 0.81 (0.71–0.90) | 0.63 (0.51–0.75) |
MutationAssessor | 843 | 0.83 (0.78–0.87) | 0.72 (0.67–0.77) |
PROVEAN | 426 | 0.69 (0.59–0.78) | 0.41 (0.31–0.50) |
PolyPhen HDIV | 286 | 0.82 (0.75–0.87) | 0.60 (0.52–0.68) |
PolyPhen HVAR | 286 | 0.81 (0.74–0.87) | 0.60 (0.52–0.68) |
SIFT | 514 | 0.79 (0.72–0.86) | 0.59 (0.51–0.66) |