Table 8. Average deviation of FP/FN rates from equilibrium (imbalance) across all GO terms in the misclassified subsection of the test dataset II and the number of terms significantly enriched in either the FP or FN subsets of the misclassified variations.
| Score | Average imbalance | Significantly enriched |
|---|---|---|
| MLP | 0.130 | 70 |
| FATHMM | 0.131 | 81 |
| PolyPhen HVAR | 0.137 | 93 |
| SIFT | 0.138 | 87 |
| sdAE | 0.143 | 82 |
| MetaLR | 0.145 | 78 |
| MetaSVM | 0.147 | 85 |
| PolyPhen HDIV | 0.153 | 100 |
| MutationAssessor | 0.161 | 99 |
| Eigen | 0.169 | 104 |
| PROVEAN | 0.170 | 100 |
| phyloP 100-way | 0.183 | 113 |
| LRT | 0.200 | 116 |
| CADD | 0.213 | 122 |
| DANN | 0.223 | 123 |
| SiPhy 29-way | 0.251 | 128 |
| MutationTaster | 0.266 | 129 |
| phastCons 100-way | 0.291 | 135 |
| GERP++ | 0.310 | 136 |