Table 1. Patient demographics.
Demographics | Normal subjects | Patients with reduced cardiac function* | P value | |
---|---|---|---|---|
Study population, n | 10 | 10 | ||
Gender (F/M) | 6/4 | 6/4 | 1.00 | |
Age (years) | 37 (20–62) | 47 (21–80) | 0.14 | |
LVEF (%) | 69.0 (3.3) | 37.0 (9.8) | <0.01 | |
LV mass index (g/m2) | 49.09 (14.78) | 68.20 (28.32) | 0.01 | |
LV EDVI (ml/m2) | 74.79 (13.03) | 122.15 (28.95) | <0.01 | |
LV ESVI (ml/m2) | 23.21 (5.63) | 78.29 (29.20) | <0.01 | |
RVEF (%) | 59.4 (7.1) | 40.0 (1.3) | <0.01 | |
RV mass index (g/m2) | 12.01 (5.21) | 14.42 (5.37) | 0.10 | |
RV EDVI (ml/m2) | 71.35 (16.00) | 96.29 (38.20) | 0.23 | |
RV ESVI (ml/m2) | 29.09 (10.84) | 59.78 (31.05) | 0.02 | |
Means LV GLS % | TomTec | -22.57 (5.13) | -11.54 (3.18) | <0.01 |
QStrain | -23.98 (2.90) | -12.14 (3.55) | <0.01 | |
Mean GCS % | TomTec | -31.44 (4.05) | -15.30 (4.48) | <0.01 |
QStrain | -33.01 (3.14) | -15.04 (5.27) | <0.01 | |
Mean GRS % | TomTec | 24.67 (5.21) | 13.78 (4.90) | <0.01 |
QStrain | 41.33 (8.54) | 21.43 (11.28) | <0.01 | |
Mean RV GLS % | TomTec | -23.74 (6.05) | -11.75 (4.25) | <0.01 |
QStrain | -26.16 (6.18) | -14.88 (4.99) | <0.01 |
Continuous variables are expressed as mean (standard deviation). Age is expressed as median (range). Volumetric results have been measured by MRI volumetry. Results for mean strain parameters are given based on three averaged measurements (R3). LVEF, left ventricular ejection fraction; LV EDVI, left ventricular enddiastolic volume; LV ESVI, left ventricular endsystolic volume; RVEF, right ventricular ejection fraction; RV EDVI, right ventricular enddiastolic volume; RV ESVI, right ventricular endsystolic volume; LV GLS, global left ventricular longitudinal strain; GCS, global left ventricular circumferential strain; GRS, global left ventricular radial strain; RV GLS, global right ventricular longitudinal strain
*as defined by reduced ejection fraction