Table 1. Gabapentin dosing recommendations in popular drug prescribing references.

High Dose*	Low Dose*	Package Insert(6)	UpToDate(5)	Medscape(4)
>600 mg/day	≤600 mg/day	Epilepsy: 900–1800 mg/day	Epilepsy: Initial dose of 900 mg/day though doses of 2,400 mg/day have been tolerated	Epilepsy: 900 mg/day (may increase to max of 1800mg/day)
		Postherpatic neuralgia: 300mg on day 1; 600mg on day 2; 900 mg on day 3 and later	Pain: 300 mg on day 1; 600 mg on day 2; 900 mg on day 3 and later to a max of 1,800 mg (as higher doses don't show greater benefit)	Postherpatic neuralgia:300mg on day 1; 600mg on day 2; 900 mg on day 3 and later
		Geriatric: Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and dose should be adjusted based on creatinine clearance values in these patients	Geriatric: Same as adult dosing	Geriatric: can titrate gradually to max of 1800mg/day
		Renal impairment (CrCl in mL/min): 30–59 = 400-1400mg/day 16–29 = 200–700mg/day ≤15 = 100–300 mg/day	Renal impairment: CrCl in mL/min): 30–59 = 400–1400 mg/day 16–29 = 200–700mg/day ≤15 = 100–300 mg/day	Renal impairment (CrCl in mL/min): 30–60 = 400-1400mg/day 15–29 = 200-700mg/day <15 = 100-300mg/day

* Low dose and high dose were defined a priori based on a variety of factors including assessment of average daily dosing in our jurisdiction.