Table 3. Association between circulating ANGPTL levels and general medical status (n = 800).
A generalized linear model was used. All variables listed were included in the model. ANGPTL, Angiopoietin-like protein; β, regression coefficient; 95% CI, 95% confidence interval; P, probability; and CKD, chronic kidney disease.
log(ANGPTL3) | log(ANGPTL4) | log(ANGPTL8) | |||||||
---|---|---|---|---|---|---|---|---|---|
β | 95%CI | P | β | 95%CI | P | β | 95%CI | P | |
Age | |||||||||
>53 | 0.066 | (0.028, 0.104) | 0.001 | -0.087 | (-0.128, -0.046) | <.001 | 0.051 | (0.003, 0.098) | 0.038 |
45–53 | 0.000 | (-0.036, 0.036) | 0.984 | 0.022 | (-0.016, 0.061) | 0.260 | -0.022 | (-0.067, 0.023) | 0.336 |
≤44 | - | - | - | - | - | - | - | - | - |
Male gender | -0.095 | (-0.130, -0.059) | <.001 | 0.148 | 0.110, 0.186) | <.001 | 0.050 | (0.006, 0.094) | 0.027 |
Smoking | 0.004 | (-0.032, 0.040) | 0.817 | 0.022 | (-0.018, 0.059) | 0.298 | -0.023 | (-0.069, 0.022) | 0.306 |
Drinking | -0.012 | (-0.040, 0.017) | 0.410 | 0.002 | (-0.028, 0.033) | 0.869 | -0.032 | (-0.069, 0.003) | 0.076 |
Obesity | -0.024 | (-0.055, 0.008) | 0.140 | -0.002 | (-0.036, 0.032) | 0.915 | 0.088 | (0.049, 0.128) | <.001 |
Impaired glycometabolism | 0.051 | (-0.005, 0.106) | 0.072 | 0.101 | 0.041, 0.160) | <.001 | -0.129 | (-0.198, -0.059) | <.001 |
Hypertension | -0.016 | (-0.048, 0.017) | 0.350 | 0.000 | (-0.035, 0.035) | 0.994 | 0.009 | (-0.032, 0.050) | 0.653 |
Dyslipidemia | -0.020 | (-0.048, 0.008) | 0.162 | 0.029 | (-0.002, 0.059) | 0.063 | 0.085 | (0.050, 0.121) | <.001 |
Hyperuricemia | 0.006 | (-0.034, 0.046) | 0.760 | 0.018 | (-0.025, 0.061) | 0.408 | 0.044 | (-0.007, 0.094) | 0.090 |
Hepatic impairment | 0.032 | (0.001, 0.063) | 0.040 | 0.037 | 0.004, 0.070) | 0.028 | 0.029 | (-0.010, 0.067) | 0.146 |
CKD | 0.001 | (-0.037, 0.058) | 0.672 | 0.026 | (-0.024, 0.077) | 0.308 | 0.029 | (-0.031, 0.089) | 0.343 |
Anemia | 0.013 | (-0.022, 0.048) | 0.478 | -0.016 | (-0.055, 0.022) | 0.401 | 0.004 | (-0.040, 0.049) | 0.850 |
Cardiac abnormality | 0.034 | (-0.081, 0.149) | 0.560 | -0.084 | (-0.207, 0.040) | 0.185 | 0.039 | (-0.105, 0.183) | 0.596 |
Inflammation | 0.077 | (0.018, 0.136) | 0.011 | -0.110 | (-0.173, -0.046) | <.001 | -0.025 | (-0.099, 0.049) | 0.512 |